Surface Inactivation of Human Coronavirus by MACOMA™ UVA-TiO2 Coupled Photocatalytic Disinfection System

There is an immense healthcare challenge and financial pressure due to the COVID-19 pandemic caused by a newly identified human coronavirus, SARS-CoV-2. Effective prevention efforts in healthcare, home, community settings highlight need for rapid, efficient, no-contact SARS-CoV-2 inactivation strategies. Here, we examined photocatalytic virucidal activity of MACOMA™ TiO2 film activated UVA-LED-12V-367 nm (MA-717836-1) lamp against HCoV-OC43, member beta coronaviruses family, like SARS-CoV-2, using quantitative RT-qPCR virus infectivity assays. The UVA radiation-responsive accelerated (decreased viral titer) compared uncoated glass surface when placed at vertical distance 1.2 feet (~14 inches) from samples 10, 30, 60 min. UVA-LED exposure both 10 30 min effectively reduced RNA copies infectious on TiO2-coated surfaces control surfaces. Importantly, completely eliminated HCoV-OC43. These results confirmed that UVA/TiO2-based disinfection system provides rapid complete tested coronavirus human-safe manner has great potential limiting spread poorly ventilated as well high-traffic public places.